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Project #561

Sodium Arsenite Studies in p53 +/- Mice

$242,259
Completed
Principal Investigator
Raymond
Tice
Research Manager
Jarmila Popovicova
Contractor
Integrated Laboratory Systems, Inc.
Constituents of Emerging Concern (CECs)
Risk Assessment
Final Report

Abstract

Evaluates the carcinogenicity of sodium arsenite as a function of hepatic methyl donor status. Also investigates the ability of sodium arsenite to promote bladder carcinogenicity and skin carcinogenicity as a function of hepatic methyl donor availability. Reports findings from investigations using heterozygous p53 deficient male mice receiving chronic administrations of arsenic in drinking water. Research partner: USEPA and ACWA. Published in 2000.

Resources

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