Project #701

Mechanisms of Carcinogenesis by Dichloroacetate (DCA) and Trichloroacetate (TCA)

$365,910
Completed
Principal Investigator
Richard
Bull
Research Manager
Richard J Karlin
Contractor
F.X. Browne, Inc.
Constituents of Emerging Concern (CECs)

Abstract

Examines whether rodent liver tumors induced by DCA and TCA are produced by a mechanism inappropriate for extrapolation to humans or by a threshold-controlled mechanism. Published in 1999.