Project 617
Dose-Response Relationships of Carcinogenic Chemicals Acting by Radical Mechanisms in Hepatocytes
$220,253
Principal Investigator
Michael Lipsky
Project Manager
Richard J Karlin
Contractor
University of Maryland
Abstract
Examines whether biological systems responsible for the production of chemical free radicals in the presence of certain chemicals commonly present in drinking water (carbon tetrachloride, chloroform, trichloroacetic acid) are responsible for the unique sensitivity of the B6C3F1 mouse to the induction of liver tumors. Completed in 1997.
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