Dec 6, 2019
Jason Mangler

What is your technology?

ANDalyze provides analytical instruments that enable real-time and point-of-use, near-lab-quality measurements of trace contaminants in water, using DNA-enzyme-based patented sensors, both portable and on-line. The U.S.EPA's Environmental Technology Verification Program (ETV) is a universal platform that offers simple, fast, inexpensive, and reliable measurement of trace metals, such as lead and copper, as well as other targets including bacteria, viruses, pesticides, and much more.


What are the benefits of implementing your technology?

AND1100 Handheld Fluorometer.

To help reduce costs, portable handheld screening tools can be used which are accurate, inexpensive, quick, and easy allowing for immediate results that are repeatable and verifiable to help identify the source and confirm remediation. However, there are additional benefits that the ANDalyze technology and product offers customers. The ANDalyze patented DNA-based technology allows users to test for almost any target contaminant including bacteria, viruses, organics, algal toxins, and much more – all using the same hand-held device – simply by changing the sensors. Unlike other technologies which react with multiple contaminants, due to the sensor selection process, catalytic DNA has much higher selectivity and at much lower concentrations. Such that most of the current ANDalyze sensors measure below 2ug/L (ppb) with the entire testing process typically taking about two minutes, with results in less than 30 seconds. Also, unlike other technologies which contain mercury sensors or which use strong acids, the ANDalyze product uses no harmful reagents and produces minimal waste which requires no special disposal.


Has the technology been tested, demonstrated, or implemented anywhere to date?

The ANDalyze technology has been extensively benchmarked against industry-standard spectral methods including the U.S.EPA's ETV Program in a full range of water types including drinking, environmental, and wastewater effluent. The U.S. EPA issued a report on the evaluation testing that concludes that ANDalyze DNAzyme products provide a valid water quality measurement alternative for certain applications, such as lead measurement in drinking water at the point of use. In addition, ANDalyze has already sold over 200 fluorometers and over 40,000 sensors to customers around the world and has worked with many universities, large industry partners, and government agencies helping to support both its industry and market validation.


Color-Coded Lead Sensor.

What are some of the next steps needed to advance the technology?

ANDalyze has commercialized the AND1100 hand-held instrument and a suite of six sensors including lead, copper, uranium, mercury, zinc, and cadmium and has nearly completed development of the AND2000 On-Line Water Quality Analyzer with the remaining work to address the improvements identified during the beta testing phase and to complete the firmware design, finalizing the user interface and standard communication protocols. Additional metals sensors have been identified and are in development. In addition, ANDalyze has already identified a sensor and created a method to measure E. coli in water helping to assure that all current sensors are transferable to the online platform and expanding our markets into testing for microbiological contaminants that may also include targets such as coliform and Legionella.


LIFT can help bring the ANDalyze technology and its onsite testing potential to the attention of key partners who either have identified current opportunities or who can help to grow the products to fit new markets and applications.
Jason Mangler
VP Sales & Marketing
ANDalyze Inc.



Jason Mangler
VP Sales/Marketing, ANDalyze Inc.